ABSTRACT
Drug-induced secondary angle closure is quite common and in the majority of cases simply stopping the medication leads to rapid reversal of the condition and resolution of glaucoma. We describe here a patient who presented with secondary angle closure glaucoma and myopia following mefenamic acid ingestion which was managed successfully by stopping the medication, symptomatic treatment and reassurance.
Subject(s)
Adult , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Choroid/diagnostic imaging , Choroid Diseases/chemically induced , Choroid Diseases/diagnosis , Diagnosis, Differential , Glaucoma, Angle-Closure/chemically induced , Glaucoma, Angle-Closure/diagnosis , Gonioscopy , Headache/drug therapy , Humans , Intraocular Pressure , Male , Mefenamic Acid/adverse effects , Mefenamic Acid/therapeutic use , Myopia/chemically induced , Myopia/diagnosis , Refraction, OcularABSTRACT
OBJECTIVE: To report three cases of delayed choroidal detachment after treatment with topical prostaglandin analogs. MATERIAL AND METHOD: Intervention three case reports. Four eyes of three patients with chronic angle closure glaucoma developed choroidal detachment after using topical prostaglandin analogs. RESULTS: Three patients with chronic angle closure glaucoma developed chroidal detachment in one week, three weeks and two years after using travoprost, bimatoprost and latanoprost respectively. All of them resolved after discontinuation of these medications. All of the eyes that developed chroidal detachment were pseudophakic. CONCLUSION: Travoprost, bimatoprost and latanoprost may lead to choroidal detachment and hypotony. Pseudophakic patients may be at high risk of the development of chroidal detachment. Topical prostaglandin analogs should be used cautiously in these patients.
Subject(s)
Administration, Topical , Aged , Amides , Choroid Diseases/chemically induced , Cloprostenol/adverse effects , Female , Glaucoma, Angle-Closure/drug therapy , Humans , Lipids/adverse effects , Middle Aged , Ocular Hypotension , Prostaglandins F, Synthetic/adverse effects , Prostaglandins, Synthetic/adverse effects , Risk Factors , Time FactorsABSTRACT
There is increasing evidence in the literature implicating the use of exogenous steroids through various routes as a risk factor for the development of idiopathic central serous chorioretinopathy (ICSC). We report a case of acute bilateral ICSC following intra-articular injection of corticosteroids.
Subject(s)
Acute Disease , Adult , Blood , Choroid Diseases/chemically induced , Female , Fluorescein Angiography , Glucocorticoids/adverse effects , Humans , Injections, Intra-Articular , Retinal Diseases/chemically induced , Tenosynovitis/drug therapy , Triamcinolone Acetonide/adverse effects , Wrist Joint/drug effectsABSTRACT
Tamoxifen is an antioestrogen drug used widely in the management of oestrogen-dependent metastatic breast carcinoma. A number of ocular complications have been described secondary to tamoxifen therapy. We report two patients, one of whom had superior ophthalmic vein thrombosis and the other who had painful proptosis and acute angle-closure glaucoma with choroidal detachment secondary to tamoxifen therapy, both of which have not been reported earlier. In both patients the signs and symptoms resolved rapidly after the discontinuation of tamoxifen therapy. Awareness of the ocular toxicity of tamoxifen is essential as prompt withdrawal can result in resolution of most of the complications.